Hello! I am Jin Wang. I am now a PhD student in Soochow University.
I am cheerful, strong sense of responsibility, treat people friendly, good at learning, innovation, work clear thinking, the implementation of strong. Through systematic study and the training in the graduate student stage, I have been proficient in molecular biology and cell biology techniques. Personal Website
August 2022 - Now
Postdoctor mayor in Toxicology in School of Public Health, Medical College of Soochow University.
July 2021 - Now
Participated in and dominated the method development and validation for the analysis of clinical samples by flow cytometry, which mainly involved immunophenotyping, activation assays by markers such as CD63/CD69/CD86, receptor occupancy analysis, and phosphoprotein detection.
February 2020 - June 2020
Teaching a course called Public Relations Practice.
January 2017 - June 2018
Engaged in ELISA and flow cytometry (FACS) related experimental operations in the Immunology Laboratory of the Department of Bioanalysis, during which he was familiar with the basic operating rules and relevant regulations of the GLP laboratory
September 2019 - Present
Soochow University
To evaluate the expression profile and function of the RNA m6A methylation reader protein YTHDC2 in lung cancer. This study was based on in vitro experiments and freely available datasets in TCGA and GEO databases.
September 2016 - July 2019
Soochow University
Our study identified miR-106b/93 as the molecular biomarker of CS-induced lung cancer, and they play a carcinogenic role by targeting SMAD7 and promoting the EMT process.
September 2012 - July 2016
Suzhou University of Science and Technology
J. Wang, L. Tan, X. Yu, X. Cao, B. Jia, R. Chen, J. Li. lncRNA ZNRD1-AS1 promotes malignant lung cell proliferation, migration, and angiogenesis via the miR-942/TNS1 axis and is positively regulated by the m(6)A reader YTHDC2. Mol Cancer. 2022 Dec 30.
J. Wang, J. Zhang, Y. Zhong, L. Qin, J. Li. Sex-dimorphic distribution and anti-oxidative effects of selenomethionine and Se-methylselenocysteine supplementation. J Food Sci. 2021 Nov 18.
J. Wang, R. Yao, Q. Luo, L. Tan, B. Jia, N. Ouyang, Y. Li, J. Tong, J. Li. miR‑200b upregulation promotes migration of BEAS‑2B cells following long‑term exposure to cigarette smoke by targeting ETS1. Mol Med Rep. 2021 Aug;24(2):562.
J. Wang, X. Tian, J. Zhang, L. Tan, N. Ouyang, B. Jia, C. Chen, C. Ge, J. Li, Postchronic Single-Walled Carbon Nanotube Exposure Causes Irreversible Malignant Transformation of Human Bronchial Epithelial Cells through DNA Methylation Changes, ACS Nano, 15 (2021) 7094-7104.
J. Wang, L. Tan, B. Jia, X. Yu, R. Yao, N. OUYang, X. Yu, X. Cao, J. Tong, T. Chen, R. Chen, J. Li. Downregulation of m6A Reader YTHDC2 Promotes the Proliferation and Migration of Malignant Lung Cells via CYLD/NF-κB Pathway. Int J Biol Sci 2021; 17(10):2633-2651
J. Wang, T. Chen, X. Yu, N. OUYang, L. Tan, B. Jia, J. Tong, & J. Li (2020). Identification and validation of smoking-related genes in lung adenocarcinoma using an in vitro carcinogenesis model and bioinformatics analysis. Journal of translational medicine, 18(1), 313.
J. Wang, X. F. Yu, N. Ouyang, S. Zhao, H. Yao, X. Guan, J. Tong, T. Chen and J. X. Li. MicroRNA and mRNA Interaction Network Regulates the Malignant Transformation of Human Bronchial Epithelial Cells Induced by Cigarette Smoke. Front Oncol. 2019; 9:1029.
J. Wang, X. F. Yu, N. OUYang, Q. L. Luo, J. Tong, T. Chen and J. X. Li. Role of DNA methylation regulation of miR-130b expression in human lung cancer using bioinformatics analysis. J Toxicol Env Heal A. 2019; 82:935-943.
J. Wang, X. F. Yu, N. OUYang, Q. L. Luo, S. Y. Zhao, X. F. Guan, T. Chen and J. X. Li. Multi-platform analysis of methylation-regulated genes in human lung adenocarcinoma. J Toxicol Env Heal A. 2019;82:37-45.
X. F. Yu, J. Wang(co-first author), O. U. N, S. Guo, H. Sun, J. Tong, T. Chen and J. Li. The role of miR-130a-3p and SPOCK1 in tobacco exposed bronchial epithelial BEAS-2B transformed cells: Comparison to A549 and H1299 lung cancer cell lines. J Toxicol Environ Health A. 2019;82:862-869.
王进,覃丽蓉,贾蓓蓓,陈涛,李建祥.AhR/CYP1B1介导香烟烟雾诱导人永生化支气管上皮细胞损伤的机制[J].环境与职业医学,2021,38(04):350-355.
钟玉婷,王进(co-first author),张佳玉,黄洁,郭仁妹,潘斐,李建祥.L-硒甲基硒代半胱氨酸对大鼠组织硒分布及GPx-1表达的影响[J].营养学报,2020,42(03):249-254.
王进,余晓凡,欧阳楠,赵诗雨,管锡菲,姚海萍,陈锐,陈涛,李建祥.甲基化调控SLIT3和SPARCL1基因在吸烟致肺腺癌中的表达及其对患者预后的影响[J].中华医学杂志,2019(20):1553-1557.
王进,马志俊,李媛媛,何俊,李聪,秦粉菊. 1-脱氧野尻霉素对睡眠剥夺小鼠认知能力的影响[J]. 营养学报,2016, 38(01): 90-92.
F. Ren, J. Wang, S. Aniagu, J. Li, Y. Jiang, & T. Chen (2020). Effects of Trichloroethylene on the Expression of Long Intergenic Noncoding RNAs in B6C3F1 Mouse Liver. Chemical research in toxicology, 33(6), 1356–1363.
X. Huang, W. Xie, X. Yu, C. Fan, J. Wang, Y. Cao, & J. Li (2019). Methyl-Cantharidimide Inhibits Growth of Human Hepatocellular Carcinoma Cells by Inducing Cell Cycle Arrest and Promoting Apoptosis. Frontiers in oncology, 9, 1234.
Y. Jiang, Z. J. Zhou, R. Fei, X. Zhou,J. Wang, Y. Z. Tao, J. X. Li and T. Chen. Role of miR-182-5p overexpression in trichloroethylene-induced abnormal cell cycle functions in human HepG2 cells. J Toxicol Env Heal A. 2019;82:920-927.
F. J. Qin, J. Zhang, L. S. Zan, W. Q. Guo,J. Wang, L. L. Chen, Y. Cao, O. X. Shen and J. Tong. Inhibitory effect of melatonin on testosterone synthesis is mediated via GATA-4/SF-1 transcription factors. Reprod Biomed Online. 2015,31:638-646.
Y. Huang, B. Jiang, Y. Xia, J. Wang, C. Ji, J. Tong, T. Chen, & Y. Jiang (2020). Downregulation of miR-133a contributes to the cardiac developmental toxicity of trichloroethylene in zebrafish. Chemosphere, 251, 126610.
June 2019: Excellent Graduated Graduate Student of Medical Department of Suzhou University
July 2020: 2019-2020 Excellent Graduate Students of Suzhou University
October 2020: National Scholarship Winner
May 2021: Excellent Graduate Graduate Student of Medical Department of Suzhou University
May 2021: Academic Model Student of Medical Department of Suzhou University
Address
199, Ren'ai Road, Industrial Park, Suzhou, China
Phone
+86-18021308280
jin.wang93@outlook.com
